If somebody is working on a new medicine, computer science helps us model those things. We have a whole group here in Seattle called the Institute for Disease Modelling that is a mix of computer science and math-type people, and the progress we're making in polio or plans for malaria or really driven by their deep insights.

Every day were saying, 'How can we keep this customer happy?' How can we get ahead in innovation by doing this, because if we don't, somebody else will.

If we have optimism without empathy then it doesn't matter how much we master the secrets of science. We're not really solving problems, we're just working on puzzles.

In my parents I saw a model where they were really always communicating, doing things together. They were really kind of a team. I wanted some of that magic myself.

You may have heard of Black Friday and Cyber Monday. There's another day you might want to know about: Giving Tuesday. The idea is pretty straightforward. On the Tuesday after Thanksgiving, shoppers take a break from their gift-buying and donate what they can to charity.

The greatest thing you can do for your competition - hire poorly.

In the same way that when the car got going, people thought it would be an electric car, people thought it would be a steam car.