... No one is less happy than I am with the performance of Microsoft stock! I've lost tens of billions of dollars this year - if you check, you'll see that's more than most people make in a lifetime!

The ability of a successful company to add functionality to its product has long been upheld.

We have two other countries, Pakistan and Afghanistan - again it's the instability that is a problem there. So over the next several years, we expect to drive the number of [polio] cases back down to zero because that is likely to be the second disease after smallpox that we completely eradicate.

The most amazing philanthropists are people who are actually making a significant sacrifice.

I want to make clear that we respect the role of government in our legal andeconomic system.

These four policy prescriptions - strengthening educational opportunities, revamping immigration rules for highly skilled workers, increasing federal funding for basic scientific research, and providing incentives for private-sector R&D - should in my view be top priorities as Congress and the Administration consider how to maintain the nation's leadership in science, technology, and innovation.

In this business, by the time you realize you're in trouble, it's too late to save yourself. Unless you're running scared all the time, you're gone.