The year I was born, 1955, the first big disease-eradication program in the world was declared for malaria. After about a decade of work, they realized that, at least in the tropical areas, they did not have the tools to get it done.

There's a basic philosophy here that by empowering...workers you'll make their jobs far more interesting, and they'll be able to work at a higher level than they would have without all that information just a few clicks away.

President [George] Bush made the U.S. absolutely the leader, between its own PEPFAR, and it's been by far the biggest Global Fund donor. That's a legacy.

We got a malaria initiative, really a phenomenal time, even though in the early stages there was some uncertainty. Then of course [Barack] Obama, although he had budget constraints, he believed in these things; a lot of new initiatives, including in agriculture.

The moral systems of religion, I think, are super important.

Like any well designed software product, Windows is designed, developed and tested as an integrated whole.

The most important 'speed' issue is often not technical but cultural. It's convincing everyone that the company's survival depends on everyone moving as fast as possible.