In most of these things our foundation is a co-funder, so I can say that a polio or an HIV vaccine, that I'm putting our resources behind it in a very big way and the U.S. government would be the best partner for those efforts.

The way to be successful in the software world is to come up with breakthrough software, and so whether it's Microsoft Office or Windows, its pushing that forward. New ideas, surprising the marketplace, so good engineering and good business are one in the same.

We can make market forces work better for the poor if we can develop a more creative capitalism-if we can stretch the reach of market forces so that more people can make a profit, or at least make a living, serving people who are suffering from the worst inequities. ... You have more than we had; you must start sooner, and carry on longer.

Security is, I would say, our top priority because for all the exciting things you will be able to do with computers - organizing your lives, staying in touch with people, being creative - if we don't solve these security problems, then people will hold back.

Scientists and companies weren't creating things like new vaccines. Now that we have this fund that's there to buy at the lowest price, but buy for those people these medicines, we see scientists everywhere coming up with those new tools.

I get more spam than anyone I know.

For Africa to move forward, you've really got to get rid of malaria.