The first big effects will be farmers that live on the edge. Today's weather, they barely get by. Their kids, a high percentage are malnourished, and so if you impose more variable weather and more heat, you're getting more floods, more droughts, and during the germination time, the high heat, most crops...do poorly when there's more heat.

The internet is just a passing fad.

The common thread for everything I do is this idea of a Web-services architecture. What does that mean? It means taking components of software and systems and having them be self-describing, so that you can aim them, ask them what their capabilities are, and communicate with them using a standard protocol.

Once you embrace unpleasant news, not as a negative but as evidence of a need for change, you aren't defeated by it. You're learning from it.

Our work in global health is about things like cutting childhood deaths, and every year we continue to make progress there.

So we can simulate Richter-10 earthquakes. We simulate 70-foot waves coming into these things. Very cool. We basically say no human should ever be required to do anything, because if you judge by Chernobyl and Fukushima, the human element is not on your side.

I'm truly saddened to learn of Steve Jobs' death. The world rarely sees someone who has had the profound impact Steve has had, the effects of which will be felt for many generations to come. For those of us lucky enough to get to work with him, it's been an insanely great honor. I will miss Steve immensely.