Another trick in software is to avoid rewriting the software by using a piece that's already been written, so called component approach which the latest term for this in the most advanced form is what's called Object Oriented Programming.

I meet people overseas that know five languages - that the only language I'm comfortable in is English.

The most important people is to pick people who like to write software and who are good at... good developers like working with each other. And they... they reinforce each other's skills.

[Melinda Gates] is a lot of fun to work with. There's some of the people skills that she's better at and cares about more. It'd be a mistake not to think of her as very numerical and interested in the science. I enjoy, if I get ahead of her, say, understanding the immune system, then we can spend a few hours, where I'm going through how amazing it is and interesting, and how that affects our creating new products, so I've always had a partner.

There are more people dying of malaria than any specific cancer.

Nobody spends any money on smallpox unless they worry about a bio-terrorist recreating it.

The barrier to change is not too little caring; it is too much complexity.