Today, we take the risk of nuclear war quite seriously, climate change not so much and epidemics least of all. But no single country, not even the United States, is well prepared. And even if one country is doing the right things to protect itself, it has to be a global thing.

Software substitution, whether it's for drivers or waiters or nurses ... it's progressing. ... Technology over time will reduce demand for jobs, particularly at the lower end of skill set. ... 20 years from now, labor demand for lots of skill sets will be substantially lower. I don’t think people have that in their mental model.

I believe in innovation and that the way you get innovation is you fund research and you learn the basic facts.

I love nuclear. It does this radiation thing that's tricky. But they're good solutions. You know, it was interesting; recently, in Connecticut this natural gas plant blew up 11 guys. It just blew them up.

Microsoft's philosophy is to 'do things better.' And Vista has given us lots of opportunity to do that.

There are a variety of techniques for breaking software down into pieces and making software development more efficient. Many of these techniques have been sort of... and everybody got excited about but very little benefit was actually derived once the thing was put into practice.

During the past two centuries, innovation has more than doubled our life span and given us cheap energy and more food. If we project what the world will be like 10 years from now without continuing innovation in health, energy or food, the picture is dark.