Sometimes we do get taken by surprise. For example, when the Internet came along, we had it as a fifth or sixth priority. It wasn't like somebody told me about it and I said, "I don't know how to spell that." I said, "Yeah, I've got that on my list, so I'm okay." But there came a point when we realized it was happening faster and was a much deeper phenomenon than had been recognized in our strategy.

There's a lot that can be done for people who are using technology in a better way.

What's amazing is, if young people understood how doing well in school makes the rest of their life so much interesting, they would be more motivated. It's so far away in time that they can't appreciate what it means for their whole life.

The phenomenal generosity of the United States in its aid budget towards health issues is the best in the world. You can look at that broadly, you can look at it in terms of HIV, the PEPFAR money which came together in a Republican administration with bipartisan support.

The government's ability to select scientists and pick things that are fairly strange, because politicians don't like failures. They're only in office a short term, and many of these things take a long time.

We have two other countries, Pakistan and Afghanistan - again it's the instability that is a problem there. So over the next several years, we expect to drive the number of [polio] cases back down to zero because that is likely to be the second disease after smallpox that we completely eradicate.

I try to make time for reading each night. In addition to the usual newspapers and magazines, I make it a priority to read at least one newsweekly from cover to cover. If I were to read what intrigues me- say, the science and business sections - then I would finish the magazine the same person I was when I started. So I read it all.