The inventory, the value of my company, walks out the door every evening.

The nuclear approach I'm involved in is called a traveling-wave reactor, which uses waste uranium for fuel. There's a lot of things that have to go right for that dream to come true - many decades of building demo plants, proving the economics are right. But if it does, you could have cheaper energy with no CO2 emissions.

Success is a miserable teacher. It tempts intelligent people to believe they cannot lose. And it is an unreliable guide to the future.

President [George] Bush made the U.S. absolutely the leader, between its own PEPFAR, and it's been by far the biggest Global Fund donor. That's a legacy.

I like my job because it involves learning. I like being around smart people who are trying to figure out new things. I like the fact that if people really try they can figure out how to invent things that actually have an impact.

Now we've got that [children's death rate] down to about 5 percent, so we've more than cut it in half, and that's because we're getting vaccines out, economic improvement also helps there, but the vaccines are why we've seen an acceleration in getting that down.

Maintaining a consistent platform also helps improve product support - a significant problem in the software industry.