You always overestimate what you can get done in a year and underestimate what you can get done in 10 years.

If your goal is to make the world a better place, one thing you can do is pick a specific challenge that you really care about. Then, learn as much as you can about it and try to volunteer your time to help an organization that is working in this area. While you're doing that, look for creative new ways to use technology to tackle parts of the problem that you come in contact with.

If I had a dollar for every time someone made fun of me in high school-oh wait, I do!

On my desk I have three screens, synchronized to form a single desktop. I can drag items from one screen to the next. Once you have that large display area, you'll never go back, because it has a direct impact on productivity.

You're never going to get the amount of CO2 emitted to go down unless you deal with the one magic metric, which is CO2 per kilowatt-hour.

Investing in innovation, which was my broad theme talking to [Warren Buffett ], that included health vaccines, it included energy and education.

Two years from now, spam will be solved.