Rules broken today become norms tomorrow.

I think it's fair to say that personal computers have become the most empowering tool we've ever created. They're tools of communication, they're tools of creativity, and they can be shaped by their user.

Even in some of our vaccine areas, like an AIDS vaccine, things have taken longer than we expected, but we have the pipeline of tools. The biological information that we have that gives us insights is fantastic.

Nobody has a guaranteed position in computer technologies business. We've done some good work, but all of these products become obsolete so fast and the structure of the business as it broadens out is going to be so different.

My wife thinks she's better than me at puzzles. I haven't given in on that one yet.

We believe the world changes when the boldest thinking is directed at the toughest problems

In most of these things our foundation is a co-funder, so I can say that a polio or an HIV vaccine, that I'm putting our resources behind it in a very big way and the U.S. government would be the best partner for those efforts.