Some people, through luck and skill, end up with a lot of assets. If you're good at kicking a ball, writing software, investing in stocks, it pays extremely well.

When you have a product that has zero sales, it is easy for people to say whatever they want about it and almost fantasize about it.

I have a nice office. I have a nice house... So I'm not denying myself some great things. I just don't happen to have expensive hobbies.

Think of business as a good game. Lots of competition and a minimum of rules. You keep score with money.

When I was young I liked taking tests. I happened to be good at it. Certain subjects came easily, like math. All the science stuff. I would just read the textbooks in the first few days of class.

The year I was born, 1955, the first big disease-eradication program in the world was declared for malaria. After about a decade of work, they realized that, at least in the tropical areas, they did not have the tools to get it done.

So not only are we saving lives now, we're creating the incentive for the breakthroughs that over the next generation will mean we can take AIDS, malaria and TB and bring those numbers dramatically down.