If you give people tools, and they use their natural abilities and their curiosity, they will develop things in ways that will surprise you very much beyond what you might have expected.

Software is inherently complicated. If you say to somebody I want an airline reservation system, to really say what you want in terms of overbooking and fares, and different airlines communicating with each or schedule changes, it's immensely complex. And so you can't write a program that's any simpler than that full specification.

Solutions to all biological problems are greatly advanced by the sequencing work and the new tools that are created.

If you think you're a really good programmer... read Knuth's Art of Computer Programming... You should definitely send me a resume if you can read the whole thing.

The challenge here is to design a system where market incentives, including profits and recognition, drive those principles to do more for the poor. I like to call this idea creative capitalism, an approach where governments, businesses, and nonprofits work together to stretch the reach of market forces so that more people can make a profit, or gain recognition, doing work that eases the world's inequities.

Thinking about impact on children meant adding to the agenda, both the R&D agenda and the delivery agenda, but it's amazing news, even in the scale of other tragedies.

AIDS we're - most of these diseases - we are down from the peak. We're down about 40 per cent from the peak and if we got the right vaccines, which are at the early stage of discovering, then the numbers would come down very dramatically. So that's why we talk about it as an emergency.