I reboot [my Windows PC] every night.

SPAM is taking e-mail, which is a wonderful tool, and exploiting the idea that it's very inexpensive to send mail.

The truth of Moore's law has made remarkable things possible. On the software side, I think natural user interfaces in all their forms are equally significant.

Online education is pretty special for two reasons. One is that you can get the very best lecture in the world and wherever you are, whenever you want, you can connect to that lecture. The other is this interactivity, where if you know a topic, you can kind of skip over it. Or if you're confused about it, [the area] where you're confused can be analyzed by software.

We're creating this alliance, GAVI, that has helped buy the vaccines that were in the rich world but not getting to the poor kids, getting a very cheap price and figuring out the cold chain, getting the delivery right, and then funding research for new vaccines. A lot of them are coming along. We've got a meningitis vaccine out, got that through large parts of Africa. That has been a huge success.

Once you embrace unpleasant news, not as a negative but as evidence of a need for change, you aren't defeated by it. You're learning from it.

We are seeing pioneers moving out to the Internet, banks that are taking transactions, retail shopping on the Internet, and although it's going to take most of a decade before most adults are turning to the Internet for a high percentage of their act