Every new change forces all the companies in an industry to adapt their strategies to that change.

Eradications are special. Zero is a magic number. You either do what it takes to get to zero and you're glad you did it; or you get close, give up and it goes back to where it was before, in which case you wasted all that credibility, activity, money that could have been applied to other things.

People always fear change. People feared electricity when it was invented, didn't they? People feared coal, they feared gas-powered engines... There will always be ignorance, and ignorance leads to fear. But with time, people will come to accept their silicon masters.

With tech companies, whoever's the leader is always questioned, you know. They say, 'Is this the end of them?' And - there's more - more times people think that's the case than it really is the case.

The world has been very careful to pick very few diseases for eradication, because it is very tough.

I'm not big on to-do lists. Instead, I use e-mail and desktop folders and my online calendar. So when I walk up to my desk, I can focus on the e-mails I've flagged and check the folders that are monitoring particular projects and particular blogs.

Our flame is taking the normal depleted uranium - the 99.3 percent that's cheap as heck, and there's a pile of it sitting in Paducah, Kentucky that's enough to power the United States for hundreds and hundreds of years. You're taking that and you are converting it to plutonium - and then you're burning that.