The most rewarding thing for me has been this affirmation for me that people are basically good and smart, and if you give them a simple tool that allows them to exhibit that behavior, they'll prove it to you every single day.

We hired a CSR person at Twitter, years before we hired our first sales person, to make sure we had a culture and impact of doing good.

When you hand good people possibility, they do great things.

I never even graduated college. I never finished learning, as it were, and I have a psychological need to be in a learning environment at all times.

Embrace your constraints. They are provocative. They are challenging. They wake you up. They make you more creative. They make you better.

I started as an artist and I had a side job moving some heavy boxes for a publishing company. They had just gotten a Mac for their art department, the department that creates the book covers. I was kind of showing the art director a thing or two about how to use a Mac. And one day everyone went out to lunch and I jumped on the computer and designed a book jacket and slipped it in the pile to go to the review board in New York. They picked my jacket and when the art director got back to Boston, he wanted to know who designed it and I said, "Me." He was like, "The box guy?"

With Twitter, it's as easy to unfollow as it is to follow.