I never even graduated college. I never finished learning, as it were, and I have a psychological need to be in a learning environment at all times.

Have confidence in your ideas before they even exist.

We actually created Twitter and Odeo at the same time. When we realized we didn't really want to be running Odeo anymore we looked around for anyone who wanted to buy Odeo, but not acquire us as a technology. But people aren't as interested in that.

The reason I really started running was for meditative purposes. I would pick some problem to have in my head while running.

Creativity is a renewable resource. Challenge yourself every day. Be as creative as you like, as often as you want, because you can never run out. Experience and curiosity drive us to make unexpected, offbeat connections. It is these nonlinear steps that often lead to the greatest work.

In any leadership position, you're always going to be disappointing somebody.

I've seen people twitter in haiku only.