[Trey Parker and Matt Stone]called me one Saturday morning and said, "Can you do an impression of Conan O'Brien?" And I said, "I don't know." Because that was really... He hadn't been on the air that long, and to be honest, I hadn't watched much of him at that point. So I went to Santa Monica to their studio and said, "Well, what does he sound like?" They said, "Well, just try it one time. Read the copy." And I read the copy one time, and they went, "Okay, that's fine. Thanks a lot, that'll do. That's perfect."

I've played myself before this ["Brent Spiner"] - and I've played myself since, for that matter - and playing yourself one of the most difficult characters you can play, 'cause God knows most of us don't know who that is.

I didn't really watch the show [Star Trek]. I still haven't seen about 150 of them. So I didn't really think of them too much in terms of episodes. I thought of them as kind of one long seven-year episode.

John Logan pretty much does the Woody Allen thing of just bringing people in and meeting them.

Timing is everything, as you know.

[Voice acting] is such an easy job. It's like stealing money, really. Which I'm always happy to do.

Joey being one of my finest performances ever. Matt LeBlanc's basically doing the same thing right now, playing himself on Episodes. When I did Joey, I really leaned on them to make me the biggest ass they possibly could, because, frankly, everyone in their heart of hearts thinks of themselves that way. Or at least I do, anyway.