The main issue [of the Scientific Revolution] is that the people in the industrialised countries are getting richer, and those in the non-industrialised countries are at best standing still: so the gap between the industrialised countries and the rest is widening every day. On the world scale this is the gap between the rich and the poor.

Most of the scientists I have known well have felt - just as deeply as the non-scientists I have known well - that the individual condition of each is tragic. Each of us is alone: sometimes we escape from solitariness, through love or affection or perhaps creative moments, but those triumphs of life are pools of light we make for ourselves while the edge of the road is black: each of us dies alone.

Civilization is hideously fragile... there's not much between us and the Horrors underneath, just about a coat of varnish.

I was moving among two groups... who had almost ceased to communicate at all, who in intellectual, moral, and psychological climate had so little in common that... one might have crossed the ocean.

The only weapon we have to oppose the bad effects of technology is technology itself. There is no other. We can't retreat into a nontechnological Eden which never existed...It is only by the rational use of technology to control and guide what technology is doing that we can keep any hopes of a social life more desireable than our own: or in fact of a social life which is not appalling to imagine.

This ability to incorporate the past gives the sharpest diagnostic tool, if one asks whether a body of knowledge is a science or not. Do present practitioners have to go back to an original work of the past? Or has it been incorporated? ... Science is cumulative, and embodies its past.

The pursuit of happiness is a most ridiculous phrase: if you pursue happiness you'll never find it.