I think about my cocaine use. I liked it. I thought it was a great drug. But I knew that if I was doing that almost exclusively, I wouldn't be able to continue to also have significant others and a wide range of other things. And I wasn't special. A number of people, including the people I was doing cocaine with, also behaved the same way.

Dopamine makes up less than one percent of the brain's neurotransmitters. It's a small portion. Dopamine is released when people are happy, angry, stressed. So it's really hard to call this specific neurotransmitter "the pleasure neurotransmitter."

Much of the early work focused on dopamine and we were really looking for rewarding sorts of effects and sure enough, we only found that. But you can destroy the main dopamine-producing structures of the brain and you can still get an animal to self-administer drugs like cocaine.

Crack in the early 1980s or mid 1980s I'm sorry is that one of the worst myth is that one hit and you're addicted for life. We saw that in 1980s and we're seeing it again with methamphetamine today, one hit and you're addicted and it simply not true, addiction requires work not the people should go out and experiment or do these themselves but the fact is that's a myth and the concern is that, it's dangerous because when people perpetuates that myths and then when young people are people actually try methamphetamine or crack cocaine and find that, that doesn't happen to them.

Take crack cocaine. Particularly in the early days of the policy, ninety percent of the people being arrested were black, even though they didn't use the drug at higher rates and even though their numbers in the general population are so low. How could that be? The thing is, you place all your resources in communities of color. And if you do that, you're going to arrest black people.

I don't want to be on the bandwagon of dogging any president or anybody in positions where they have all these different constituencies.

My critique of how we deal with drugs in society is just that - that we use these anecdotes to apply to everyone and the anecdotes are not representative.