Writing a novel is like trying to solve a very long mathematical equation. Changing anything can change everything else.

There are in fact 100 billion galaxies, each of which contain something like a 100 billion stars. Think of how many stars, and planets, and kinds of life there may be in this vast and awesome universe.

Because men, compared to male chimps, have such relatively small testicles (large testicles indicate a species where many males mate, one after the other, with the same female), we might guess that promiscuous societies were uncommon in the immediate human past.

The fact that someone says something doesn't mean it's true. Doesn't mean they're lying, but it doesn't mean it's true.

What is called for is an exquisite balance between two conflicting needs: the most skeptical scrutiny of all hypotheses that are served up to us and at the same time a great openness to new ideas. If you are only skeptical, then no new ideas make it through to you. On the other hand, if you are open to the point of gullibility and have not an ounce of skeptical sense in you, then you cannot distinguish useful ideas from the worthless ones.

If you want to make a [rhubarb] pie from scratch, first you have to create the universe.

The universe seems neither benign nor hostile, merely indifferent.