In Western Europe and North America some things are better than they were - at least relative to their moral nadirs - such as labour legislation, the opening of the professions to women, intolerance for domestic violence, but so much is still morally unacceptable - the weapons trade, cruel and unusual punishment, economic parasitism.

In the academic setting, you take (typically) lonely, interesting middle-aged men and beautiful, intelligent young women, and everybody's motivations for display and conquest are engaged to the max. Sublimated, this can be a powerful force for the good - Plato had a lot to say about that - but acted upon it can bring evils without end.

For the chemists, who wanted to manufacture new medicines and elixirs and transform base substances into noble ones, the notion that there was no metaphysical barrier to doing so - it was just a matter of getting the particles into new arrangements - was encouraging. That was the Baconian programme.

Moral claims aren't, as a class, truth-value apt or not.

There's Hobbes, who understood in the 1640s that the sovereign is not an appointee of God, or even a figure of superior virtue and wisdom, but just a functional device whose role is to keep people from hurting and killing each other.

Atomism had no absolute 'above' and 'below' and no such rulers, so favoured the undersranding of justice as an agreement amongst equals.

Maybe we will get to this point and reach a decision one way or the other with 'Human cloning is acceptable,' but I doubt that it is ever going to happen for 'It is morally permissible to eat shrimp' or with the general formula 'Adultery is wrong,' whose intended extension is again very unclear.