Epicurus thought that friendship and conviviality, which require present attention rather than being in an alcoholic stupor, as well as trying to understand and explain things, were the greatest sources of satisfaction in life, so there go most drugs.

Epicureanism did inspire libertine culture in isolated sects, but Epicurus himself rejected an ethics of sensory indulgence, and he would have disowned latter-day 'Epicureanism' as a fussy, expensive, unphilosophical approach to eating and drinking.

If you live in an acquisitive society you are likely to be acquisitive, but it isn't deeply rooted in human nature, except in the sense that it's deeply rooted to be psychologically receptive to your peers and to advertising.

Leibniz accepted the argument that there must be indestructible simple entities if there is to be a complex world, but Epicurean morals and politics and anti-theology dismayed him. His 'monadology' which said that the true atoms of nature were unextended 'living mirrors,' was an imaginative and beautiful system, and even in many ways more modern than Epicurean atomism, than Epicurean atomism, but there was a reactionary aspect to it.

I have to say that some philosophers such as the late Bernard Williams, and I would include myself in this group, would say that tranquillity is overrated as the goal of life.

The (atomic) soul is mortal, and the best life is the one with the least pain and the most pleasure.

There's Hobbes, who understood in the 1640s that the sovereign is not an appointee of God, or even a figure of superior virtue and wisdom, but just a functional device whose role is to keep people from hurting and killing each other.