As followers of natural science we know nothing of any relation between thoughts and the brain, except as a gross correlation in time and space.
Charles Scott SherringtonIf we denote excitation as an end-effect by the sign plus (+), and inhibition as end-effect by the sign minus (-), such a reflex as the scratch-reflex can be termed a reflex of double-sign, for it develops excitatory end-effect and then inhibitory end-effect even during the duration of the exciting stimulus.
Charles Scott SherringtonFurther study of central nervous action, however, finds central inhibition too extensive and ubiquitous to make it likely that it is confined solely to the taxis of antagonistic muscles.
Charles Scott SherringtonThis integrative action in virtue of which the nervous system unifies from separate organs an animal possessing solidarity, an individual, is the problem before us.
Charles Scott Sherrington