If we denote excitation as an end-effect by the sign plus (+), and inhibition as end-effect by the sign minus (-), such a reflex as the scratch-reflex can be termed a reflex of double-sign, for it develops excitatory end-effect and then inhibitory end-effect even during the duration of the exciting stimulus.
Charles Scott SherringtonThat our being should consist of two fundamental elements [physical and psychical] offers I suppose no greater inherent improbability than that it should rest on one only.
Charles Scott SherringtonWith the nervous system intact the reactions of the various parts of that system, the 'simple reflexes', are ever combined into great unitary harmonies, actions which in their sequence one upon another constitute in their continuity what may be termed the 'behaviour'.
Charles Scott SherringtonThe terminal path may, to distinguish it from internuncial common paths, be called the final common path. The motor nerve to a muscle is a collection of such final common paths.
Charles Scott SherringtonThat a strong stimulus to such an afferent nerve, exciting most or all of its fibres, should in regard to a given muscle develop inhibition and excitation concurrently is not surprising.
Charles Scott Sherrington