I think substitution is a huge part of acting, but I don't personalise my work that much.

Remember I came to Albuquerque to do a hair and makeup test and wardrobe fitting; you guys were already shooting. It's tough when the movie's already started and you kind of show up. You're the new kid on the block. I walked onto the set and Tommy [Lee Jones] was about to do the scene. I just kind of walked up to him. I was shaking, but I just gave him this big hug and he just had nothing to say. He was like, 'Gotta go to work now.' I had a great time working with him."

I have very talented people dress me and put my makeup on, stuff like that. But I do love that look, and I think it's maybe because I grew up on that old glamour.

I was going to go to Macchu Picchu and then I just ended up working the whole year.

I grew up during apartheid; there was never a day in South Africa that was just great. I love that I've had success as an actor and producer, but I know the thing my children will know most about is the work I've done with HIV. Success in life is all about humanity.

People always say to me, "What's wrong with Hollywood? They don't want to make female-driven movies." And that's not where the problem lies. It lies with us, in society. When we make these movies, nobody goes to see them.

I do think that when you're specifically working in a country like South Africa, you have to be able to be aware of the cultural truth of what people are raised in and believe in and how they function within their society.