Our role is to develop techniques that allow us to provide emergency life-saving procedures to injured patients in an extreme, remote environment without the presence of a physician.

The cool things about space is when you put your pants on here, you can put them on two legs at a time.

When I stand on the edge of a cliff or right at the edge of a building or something, it's one of the few things that gives me kind of a deep, overwhelming, irrational fear where it affects my physiology.

Fatherhood is the unending imperfect task of turning yourself into your dad while secretly maintaining the unbridled elation of your boyhood

Other anatomical changes associated with long-duration space flight are definitely negative: the immune system weakens, the heart shrinks because it doesn't have to strain against gravity, eyesight tends to degrade, sometimes markedly (no one's exactly sure why yet). The spine lengthens as the little sacs of fluid between the vertebrae expand, and bone mass decreases as the body sheds calcium. Without gravity, we don't need muscle and bone mass to support our own weight, which is what makes life in space so much fun but also so inherently bad for the human body, long-term.

In all of the movie portrayals, a spacewalking suit seems sort of insignificant, like a pair of shorts and a T-shirt. No one thinks much about it. But it's a spaceship, not a spacesuit, an entire life-support mechanism that's incredibly complex and cumbersome. It's very difficult to put on and off. You have to run it the whole time you are wearing it, and it redefines how you move. It's like if you put on a wetsuit and a snowmobile suit and froze yourself solid and then tried to go and do work.

For the last several years and culminating in six months in orbit next year, I've been training for my third space flight. This one is almost in a category completely different than the previous two, specifically to live in on the space station for six months, to command a space ship and to fly a new rocket ship.