I've been lucky enough to fly to space twice.

It is spectacular. From about five minutes in, when we knew for sure that we were going to have the weather to go, the smile on my face just got bigger and bigger, and I was just beaming through the whole launch. I mean, it is just an amazing ride.

In any new situation, whether it involves an elevator or a rocket ship, you will almost certainly be viewed in one of three ways. As a minus one: actively harmful, someone who creates problems. Or as a zero: your impact is neutral and doesn't tip the balance one way or the other. Or you'll be seen as a plus one: someone who actively adds value. Everyone wants to be a plus one, of course. But proclaiming your plus-oneness at the outset almost guarantees you'll be perceived as a minus one, regardless of the skills you bring to the table or how you actually perform.

I want to know: How does a space suit on Mars work? Show me how it is pressurized, and how it is cooled. What's the glove design? None of that stuff can be bought off the rack. It does not exist. You can't just go to SpaceMart and buy those things.

No one ever accomplished anything great sitting down.

If you start thinking that only your biggest and shiniest moments count, you're setting yourself up to feel like a failure most of the time.

Our role is to develop techniques that allow us to provide emergency life-saving procedures to injured patients in an extreme, remote environment without the presence of a physician.