In any new situation, whether it involves an elevator or a rocket ship, you will almost certainly be viewed in one of three ways. As a minus one: actively harmful, someone who creates problems. Or as a zero: your impact is neutral and doesn't tip the balance one way or the other. Or you'll be seen as a plus one: someone who actively adds value. Everyone wants to be a plus one, of course. But proclaiming your plus-oneness at the outset almost guarantees you'll be perceived as a minus one, regardless of the skills you bring to the table or how you actually perform.

In all of the movie portrayals, a spacewalking suit seems sort of insignificant, like a pair of shorts and a T-shirt. No one thinks much about it. But it's a spaceship, not a spacesuit, an entire life-support mechanism that's incredibly complex and cumbersome. It's very difficult to put on and off. You have to run it the whole time you are wearing it, and it redefines how you move. It's like if you put on a wetsuit and a snowmobile suit and froze yourself solid and then tried to go and do work.

Our role is to develop techniques that allow us to provide emergency life-saving procedures to injured patients in an extreme, remote environment without the presence of a physician.

My optimism and confidence come not from feeling I'm luckier than other mortals, and they sure don't come from visualizing victory. They're the result of a lifetime spent visualizing defeat and figuring out how to prevent it. Like most astronauts, I'm pretty sure that I can deal with what life throws at me because I've thought about what to do if things go wrong, as well as right. That's the power of negative thinking.

It’s not enough to shelve your own competitive streak. You have to try, consciously, to help others succeed.

For the last several years and culminating in six months in orbit next year, I've been training for my third space flight. This one is almost in a category completely different than the previous two, specifically to live in on the space station for six months, to command a space ship and to fly a new rocket ship.

The cool things about space is when you put your pants on here, you can put them on two legs at a time.