The city needs a car like a fish needs a bicycle.

I think in our lifetime, that level of acceptance of "well, we couldn't do any better," won't be tolerated. We're going to start to see individual therapies customized for individual patients, and it's going to change the way people get healthcare.

New ideas in technology are literally a dime-a-dozen, or cheaper than that

I think an education is not only important, it is the most important thing you can do with your life.

[Chuck's wife] was standing behind me at the time and she said, 'Chuck hasn't fed himself in 19 years. So, you've got a choice: We keep the arm, or you keep Chuck.'

The word entrepreneur is associated with success and adventure. From my life, the only thing I can tell you that's consistently associated with entrepreneurship is failure, and the only thing consistently associated with invention is frustration. There is a long road between the idea and the reality.

We live in a world where virtually everybody expects there's going to be some reasonable therapy for virtually any situation.