No one employed [ chaos] better than Jim Henson, by the way, on The Muppets. He had all these chicken Muppets that just brought in the most glorious chaos to whatever scene they were a part of.

I'm pretty sure no one's reading action scripts saying, 'This has got to be Ed Helms.'

People who grew up in New York City or Los Angeles tend not to even understand what goes on in the rest of the country. I'm really glad to have grown up in an environment where I actually was kind of a weirdo because I was obsessed with comedy and movies and stuff.

There are certain relationships in our lives that implode, and it can feel really inexplicable and terrifying. You don't know why, and sometimes relationships end for reasons that one person keeps from the other person, and it's just totally unclear, and it just goes south and it's heartbreaking.

This word gets overused in describing actors but I think it applies to Mike [Tyson] in this case - he was totally fearless. He jumped in and played with us comedically and improvised a lot. A lot of jokes in those scenes with him are from him improvising.

When we were not shooting [The Hangover] we were sleeping, so pretty much every waking moment we spent together. And, you know, Bradley [Cooper], Zach [Galifianakis] and I were acquaintances before the movie started but we became good friends very quickly and spent so much time together that it was just inevitable we were either going to really hate each other or really like each other. Thank god it turned out to be the latter.

There are currently more political parties in Iraq than unbombed buildings to hold them.