I'm pretty sure no one's reading action scripts saying, 'This has got to be Ed Helms.'

We spent six weeks there [in Vegas]. The only thing crazy that I did was shoot that movie [The Hangovers]. The stuff in that movie is way crazier than anything I might have done, drunk one night in Vegas. I mean we did it for real in the movie, so that's as crazy as it got.

All I knew is that I loved movies and comedy and TV, and I wanted to perform. I made a bunch of shorts and movies in college, and that was always fun too. I directed some plays in college. It was taking it all in and trying to immerse myself in as much of it as possible.

Todd [Phillips] doesn't care. That's part of his genius as a director, he will say anything to anybody.

There are certain relationships in our lives that implode, and it can feel really inexplicable and terrifying. You don't know why, and sometimes relationships end for reasons that one person keeps from the other person, and it's just totally unclear, and it just goes south and it's heartbreaking.

I think that music at inappropriate times with inappropriate volumes can be the funniest thing ever.

I didn't mention the tooth thing to anyone until it became clear that...we started to discuss just taking it out of the movie [The Hangover] because we couldn't find anything that worked and they couldn't afford to do a full like digital effect. So that's when I called my dentist and it worked out.