One of the things that got me transitioning from physical science to brain science was asking, Why do we understand so much about the universe?

Suppose there are some things that we don't understand about the universe, but if you understand human intelligence and you understand the gaps in our abilities to think about things, maybe we can engineer in a computer more advanced intelligences that can help augment our ability to think.

A big part of my job is to remember failure, and reboot failure, when the timing is right.

It's surprising that the world is understandable to the extent that it is.

There are many things that we still don't understand about the universe, right? Einstein struggled to bring quantum mechanics and gravity together and never succeeded, and that's a problem that to this day is not well understood. Well, maybe to comprehend some of these things, we need to augment our intelligence. If we do, who knows?

I think the definition will change as we learn more, but my working definition of solving the brain is: one, we can model, maybe in a computer, the processes that generate things like thoughts and feelings, and two, we can understand how to cure brain disorders, like Alzheimer's and epilepsy. Those are my two driving goals. One is more human-condition oriented, and one more clinical.

I often try to think about, What sounds like a bad idea, but if you find the right plan of attack, it's actually a really good idea? I spend a lot of time really trying to systematically tackle problems from different angles.