The three main leads [in Townies] were Lauren [ Graham] and Jenna [Elfman] and Molly [Ringwald], and then Ron Livingston was on it as well. There was a lot of people to write funny stuff for.

The Andromeda strain is a killer disease that they've got to prevent from spreading to being 100 percent contagious. It's another one where we're racing to save humanity.

Mental illness is the last frontier. The gay thing is part of everyday life now on a show like 'Modern Family,' but mental illness is still full of stigma. Maybe it is time for that to change.

Every actor has periods of their life that are a little less busy than others, and that was just a time when I needed that. And to be back on a sitcom stage, with Julia [ Louis-Dreyfus], was really, really fun.

I was playing this sort of asshole actor [in The Jenny McCarthy Show]. And we shot the pilot, and it was a guaranteed go. It was going to be 24 [episodes] on the air. No questions from NBC. And we shot the pilot, and I was in Toronto doing a movie, and I got a call saying they cut the character, that I was off the show.

I was going to be the hero of the movie [The Lost World]. I had to speak up and be like, "Shouldn't I be the one doing that?

I think there's a certain objectivity that comes from being Canadian. You're partly British and partly American; you have a good bird's-eye view of both countries. So much of the comedy that comes out of Canada is impersonation - it's less 'look at me' than it is 'look at me playing other people.