I think we all realize that anyone can - and has - gotten AIDS. So there's obviously still a lot to be done.

I grew up on M*A*S*H and All In The Family and Cheers. And then around this time, this would have been '95, '96, I was so into Friends and Mad About You, the idea of being on a sitcom became a very real thing that I wanted. It was not so much a relief. It was really exciting. It's an amazing thing to be in front of an audience.

[Trust Me] was TNT, and they were really supportive of the show, but in the end they just didn't feel it was their audience. I never really understood why we didn't get a longer run at it, because it was Griffin Dunne and Monica Potter. Just a really strong cast.

[The Lost world] was a learning experience. I remember we were shooting a scene in which I dive out of a boat into a river to save the kid that's in the movie. And there's no mention of a stuntman, and I was like, "No, I'll go in." Nobody questioned. I never asked if maybe there was malaria in the water. And I was wearing these tall boots.

Every actor has periods of their life that are a little less busy than others, and that was just a time when I needed that. And to be back on a sitcom stage, with Julia [ Louis-Dreyfus], was really, really fun.

I was going to be the hero of the movie [The Lost World]. I had to speak up and be like, "Shouldn't I be the one doing that?

The Andromeda strain is a killer disease that they've got to prevent from spreading to being 100 percent contagious. It's another one where we're racing to save humanity.