I had the analysis of a million or so SNPs [single nucleotide polymorphisms] just to see what was there. That's partly because I was writing a book about DNA and personalized medicine and I thought it would be a little bit disingenuous to talk about what could be done without actually having the experiment done on yourself.
Francis CollinsResearch is so unpredictable. There are periods when nothing works and all your experiments are a disaster and all your hypotheses are wrong.
Francis CollinsWhen a drug comes out [that's broadly prescribed] there are going to start to be a lot of people on it [in a million person cohort] and you might get therefore an early signal of something unexpected that hadn't come through in the clinical trials. And I'm sure [drug companies] would love it if, in fact, FDA, recognizing that, would say, OK, maybe you don't have to do your trial with 30,000 people because we're going to find out shortly after registration because we'll have a lot of people taking the drug and we'll be able to see what happened using PMI.
Francis CollinsTo get our universe, with all of its potential for complexities or any kind of potential for any kind of life-form, everything has to be precisely defined on this knife edge of improbability. [Y]ou have to see the hands of a creator who set the parameters to be just so because the creator was interested in something a little more complicated than random particles.
Francis Collins[Decoding the human genome sequence] is the most significant undertaking that we have mounted so far in an organized way in all of science. I believe that reading our blueprints, cataloguing our own instruction book, will be judged by history as more significant than even splitting the atom or going to the moon.
Francis Collins