The meaning of this observation is unclear, but it raises the unfortunate possibility of ambiguous triplets; that is, triplets which may code more than one amino acid. However one would certainly expect such triplets to be in a minority.
Francis CrickThis seems highly likely, especially as it has been shown that in several systems mutations affecting the same amino acid are extremely near together on the genetic map.
Francis CrickMy own prejudices are exactly the opposite of the functionalists': "If you want to understand function, study structure".
Francis Crick