It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
Francis CrickA knowledge of the true age of the Earth and of the fossil record makes it impossible for any balanced intellect to believe in the literal truth of every part of the Bible in the way that fundamentalists do.
Francis CrickAgain the message to experimentalists is: Be sensible but don't be impressed too much by negative arguments. If at all possible, try it and see what turns up. Theorists almost always dislike this sort of approach.
Francis Crick