A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.
Francis CrickConsciousness is somehow a by-product of the simultaneous, high frequency firing of neurons in different parts of the brain. It's the meshing of these frequencies that generates consciousness, just as tones from individual instruments produce the rich, complex, & seamless sounds of a symphony orchestra
Francis CrickIt now seems certain that the amino acid sequence of any protein is determined by the sequence of bases in some region of a particular nucleic acid molecule.
Francis CrickUnfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were only one triplet for each amino acid.
Francis Crick