Life cannot have had a random beginning. ... The trouble is that there are about two thousand enzymes, and the chance of obtaining them all in a random trial is only one part in 10 to the 40,000 power, an outrageously small probability that could not be faced even if the whole universe consisted of organic soup.
Fred HoyleImagine 1050 blind persons each with a scrambled Rubik's cube, and try to conceive of the chance of them all simultaneously arriving at the solved form. You then have a chance of arriving by random shuffling, of just one of the many biopolymers on which life depends. The notion that not only the biopolymers but the operating program of a living cell could be arrived at by chance in a primordial organic soup here on the Earth is evidently nonsense of a high order.
Fred HoyleA common sense interpretation of the facts suggests that a superintellect has monkeyed with physics.
Fred HoyleOnce we see, however, that the probability of life originating at random is so utterly minuscule as to make it absurd, it becomes sensible to think that the favorable properties of physics, on which life depends, are in every respect deliberate.... It is, therefore, almost inevitable that our own measure of intelligence must reflect higher intelligence -even to the limit of God.
Fred Hoyle