It is emphatically the case that life could not arise spontaneously in a primeval soup of any kind.... Furthermore, no geological evidence indicates an organic soup ever existed on this planet. We may therefore with fairness call this scenario the myth of the pre-biotic soup.
Fred HoyleThere are many ways of knocking electrons out of atoms. The simplest is to rub two surfaces together.
Fred HoyleImagine 1050 blind persons each with a scrambled Rubik's cube, and try to conceive of the chance of them all simultaneously arriving at the solved form. You then have a chance of arriving by random shuffling, of just one of the many biopolymers on which life depends. The notion that not only the biopolymers but the operating program of a living cell could be arrived at by chance in a primordial organic soup here on the Earth is evidently nonsense of a high order.
Fred HoyleLife cannot have had a random beginning. ... The trouble is that there are about two thousand enzymes, and the chance of obtaining them all in a random trial is only one part in 10 to the 40,000 power, an outrageously small probability that could not be faced even if the whole universe consisted of organic soup.
Fred Hoyle