Most theoretical work since the proposals of Hebb (1949) and Hayek (1952) has relied upon particular forms of dependent synaptic rules in which either pre- or postsynaptic change is contingent upon closely occurring events in both neurons taking part in the synapse.
Gerald EdelmanYour brain develops depending on your individual history. What has gone on in your own brain and its consciousness over your lifetime is not repeatable, ever - not with identical twins, not even with conjoined twins.
Gerald EdelmanEvolution works by selection, not by instruction. There is no final cause, no teleology, no purpose guiding the overall process
Gerald EdelmanA knowledge of brain science will provide one of the major foundations of the new age to come. That knowledge will spawn cures for disease, new machines based on brain function, further insights into our nature and how we know.
Gerald EdelmanThe analogy between the mind and a computer fails for many reasons. The brain is constructed by principles that assure diversity and degeneracy. Unlike a computer, it has no replicative memory. It is historical and value driven. It forms categories by internal criteria and by constraints acting at many scales, not by means of a syntactically constructed program. The world with which the brain interacts is not unequivocally made up of classical categories.
Gerald Edelman