Science, like art, religion, commerce, warfare, and even sleep, is based on presuppositions.

It takes two to know one.

People are going to have to make themselves predictable, or the machines will get angry and kill them.

But epistemology is always and inevitably personal. The point of the probe is always in the heart of the explorer: What is my answer to the question of the nature of knowing?

It is of first-class importance that our answer to the Riddle of the Sphinx should be in step with how we conduct our civilisation, and this should in turn be in step with the actual workings of living systems.

Desired substance, things, patterns, or sequences of experience that are in some sense "good" for the organism - items of diet, conditions of life, temperature, entertainment, sex, and so forth - are never such that more of the something is always better than less of the something. Rather, for all objects and experiences, there is a quantity that has optimum value. Above that quantity, the variable becomes toxic. To fall below that value is to be deprived.

All experience is subjective.