If you start asking how do we make life meaningful and life never ends, then you get into sort of these terrible sort of metaphysical quandaries and it gets really, really bleak looking.

In the 1950s that tug-of-war between the expectations of behaving normally and the limitlessness of thinking freely produces some very strange characters.

I know I'm a better editor than I was when I began, twenty years ago. I'm less scared of the text, I'm less scared of the writer, and, crucially, I no longer believe that I have to leave my mark on every story.

There are times I wish I didn't have a job, even though I love my job: I get to work with interesting, eccentric colleagues and equally interesting and eccentric subject matter, both of which are rarities. But, naturally, I would treasure having more freedom someday: of time and of movement. Will I always have a full-time job? I don't know. But I do know that I need to spend at least part of my week in an office, with other people.

Now, almost twenty years since my last job in book publishing, I know that there are far more socially inept people in book than in magazine publishing. At the time, however, I just didn't feel I was enough: smart enough, savvy enough, well read enough, educated enough, charming enough. Much of this was probably because I was very naive, and didn't really know how to behave in an office. This made me a terrible assistant, which in turn made me a terrible junior book editor.

I'm not sure a person ever really reveals the whole of himsels or herself to another person, and I'm not sure we should. Or rather, just because you don't, it doesn't mean you can't have a meaningful relationship with another person. It's important to remember that this idea of confessing your most shameful, embarrassing stories and self to someone else as an expression of love and intimacy is a relatively recent phenomenon, and a new definition of what it means to be close to someone. After all, the self is by its nature secretive.

I always wanted to be a scientist. I don't really have any writer friends. The process of being a writer is much more interior than being a scientist, because science is so reactionary. I think that all research scientists think of themselves as belonging to a grand tradition, building on work that has been worked on since the very beginning of science itself. Whereas I'm not sure writers think of themselves in the same way.