There's something very edgy about Bill Murray out there improvising.

Most people live somewhere on the spectrum of anxiety and depression.

I did a comedy with Al Franken about his character Stuart Smalley, which was really about alcoholism and addiction and codependency. It had some painful stuff in it. When we showed it to focus groups, some of them actually said, "If I want to see a dysfunctional family, I'll stay home."

I'm terrified beyond the capacity for rational thought.

I'd like to think I'd never do a gratuitous fart joke.

I loved writing and performing, but the idea of doing it for a living seemed so remote. But I eventually let it devolve to the point where it was the only thing I could do.

I'm sure that the liability for doing a tracheotomy would be tremendous. You make one mistake, and it's over. Most doctors won't even do it.