I knew that there was an aspect to this story that was beyond the typical and that it was something very important about America, about our culture, and about bringing a story to a new generation that perhaps didn't know the details of it, (and) hadn't had the visceral experience that this film is [42].

My goal was just to work regularly. I didn't ever expect to be rich or famous. I wanted to be a working character actor.

Hell of a thing when a man's got good health, plenty of money and absolutely nothing to do.

Because the character is a fiction, he's a composite of other contributors to the science that brought this enzyme therapy through the process. We had the opportunity to make him up out of those things that helped tell the story. We wanted to create both ally and antagonist for John [in the Extraordinary measures].

Really, what are the options? Levi's or Wranglers. And you just pick one. It's one of those life choices.

Work hard and figure out how to be useful and don't try to imitate anybody else's success. Figure out how to do it for yourself with yourself.

I was always very grateful I was never hot. In the entire length of my career, I haven't been the most adored.