Nothing shocks me. I'm a scientist.

I realized early on that success was tied to not giving up.

I have children. I have other concerns. I have other focuses. I really feel very sympathetic and I would love to be able to help but I don't see this as the opportunity, having done 'Extraordinary measures', for me to suddenly leap on a soap box and begin to talk about the pharmaceutical industry or the desperate plight of sick children. I do what I can in my world but I don't have the bona fides to do that right now.

The job's always the same. It involves helping to tell the story and creating an alloy between character and story that serves the film.

You know how a woman gets a man excited? She shows up.

It's always nice to anticipate working in something that you know people will have an appetite for.

I'm ambitious for is to not get caught 'acting'. I want to really feel the role and not let people see the process, or to let them stand back and admire it, because I think that does finally get in the way.