I would do 'American Splendor' and 'About Schmidt' again in a heartbeat.

I have not spent years in therapy; I tried therapy in my mid-twenties, and it did not go very well. I just thought, 'This is so not for me. I would rather talk to one of my girlfriends.' I'm not at a point in my life when I'm analyzing too much. I have young children, and I'm just pretty much crazed.

To play Hillary Clinton? I'm kind of winging it. No, are you kidding me? I prepared obsessively. I mean, as much as I could in the time that I was given. Of course, with someone like Hillary Clinton, obviously, anything you want is on YouTube and at your fingertips there.

The older you get, the more you realize that the way you look is a reflection of how you treat yourself.

I've been lucky. I've made films that I really like. It's been a combination of what comes to me and what I choose. I've gone after lots of things that I didn't get, pet projects that everybody ends up chasing after. Really, you're lucky if you get anything.

I haven't frequented a nail salon in a long time.

Every summer my husband and I pack our suitcases, load our kids into the car, and drive from tense, crowded New York City to my family's cottage in Maine. It's on an island, with stretches of sea and sandy beaches, rocky coasts, and pine trees. We barbecue, swim, lie around, and try to do nothing.