I am very, very aware at all times. I'm watching myself, I'm listening to myself, I'm judging myself, critiquing myself all the time, and I will know when I do something and I will immediately say, "Can I do another one, because I didn't quite get that thing," or that I wanted to do something there and it didn't quite work.

One thing House needs Wilson for is vanity. He needs someone to laugh at his jokes.

[...] and as I walked, I tried to see the funny side. It wasn't easy, and I'm still not sure that I managed it properly, but it's just something I like to do when things aren't going well. Because what does it mean, to say that things aren't going well? Compared to what? You can say: compared to how things were going a couple of hours ago, or a couple of years ago. But that's not the point. If two cars are speeding towards a brick wall with no brakes, and one car hits the wall moments before the other, you can't spend those moments saying that the second car is much better off than the first.

To tell you the truth, the older I get, the less I know. I keep meeting people, both older and younger, who seem to have accrued so much more knowledge or expertise or certainty about who they are and the jobs they do. I just marvel at it.

I don't talk like House, or walk like him. I certainly don't think like him. I don't like to think for more than 15 minutes at a stretch actually; I am a fragile flower.

I think maybe even one of the reasons I became an actor was actually to hide. I mean, it sounds paradoxical because, of course, people are standing up in a public place and encouraging other people to look at them. So that's not the conventional definition of hiding.

It's a terrible thing, I think, in life to wait until you're ready. I have this feeling now that actually no one is ever ready to do anything. There is almost no such thing as ready. There is only now. And you may as well do it now. Generally speaking, now is as good a time as any.