Newton's Third Law of Conversation, if it existed, would hold that every statement implies an equal and opposite statement. To say that I'd turned the offer down raised the possibility that I might not have done.

I'm finding it increasingly difficult to simply walk down the street. In New York, I dashed in to buy a big pair of sunglasses to conceal myself, but the guy behind the counter shouted 'Hey! It's Dr. House.'

I didn't realize House would be the central character, more the bitter comic relief appearing occasionally. I relish his wounded nature - the lameness, the scarred Byronic hero.

I get anxious about a lot of things, that's the trouble. I get anxious about everything. I just can't stop thinking about things all the time. And here's the really destructive part - it's always retrospective. I waste time thinking of what I should have said or done.

Screenwriting is the most prized of all the cinematic arts. Actually, it isn't, but it should be.

People will survive, and they will find happiness. Happiness only comes when you're not looking for it.

I think good-looking people seldom make good television. And American television studios almost concede before they start: 'Well, it won't be good, but at least it'll be good-looking. We'll have nice-looking girls in tight shirts with F.B.I. badges and fit-looking guys with lots of hair gel vaulting over things.'